골밀도 상태에 따른 검사자의 재현성 평가

• 영문명: The Precision Test Based on States of Bone Mineral Density
• 발행기관: 대한핵의학기술학회
• 저자명: 유재숙(Jae sook Yoo) 김은혜(Eun Hye kim) 김호성(Ho Seong Kim) 신상기(Sang Ki Shin) 조시만(Si Man Cho)
• 간행물 정보: 『핵의학기술』Vol.13 No.1, 67~72쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2009.05.30

영문 초록

Purpose: ISCD (International Society for Clinical Densitometry) requests that users perform mandatory Precision test to raise their quality even though there is no recommendation about patient selection for the test. Thus, we investigated the effect on precision test by measuring reproducibility of 3 bone density groups (normal, osteopenia, osteoporosis). Materials and Methods: 4 users performed precision test with 420 patients (age: 57.8±9.02) for BMD in Asan Medical Center (JAN-2008 ~ JUN-2008). In first group (A), 4 users selected 30 patient respectively regardless of bone density condition and measured 2 part (L-spine, femur) in twice. In second group (B), 4 users measured bone density of 10 patients respectively in the same manner of first group (A) users but dividing patient into 3 stages (normal, osteopenia, osteoporosis). In third group (C), 2 users measured 30 patients respectively in the same manner of first group (A) users considering bone density condition. We used GE Lunar Prodigy Advance (Encore. V11.4) and analyzed the result by comparing %CV to LSC using precision tool from ISCD. Check back was done using SPSS. Results: In group A, the %CV calculated by 4 users (a, b, c, d) were 1.16, 1.01, 1.19, 0.65 g/cm2 in L-spine and 0.69, 0.58, 0.97, 0.47 g/cm2 in femur. In group B, the %CV calculated by 4 users (a, b, c, d) were 1.01, 1.19, 0.83, 1.37 g/cm2 in L-spine and 1.03, 0.54, 0.69, 0.58 g/cm2 in femur. When comparing results (group A, B), we found no considerable differences. In group C, the user_1’s %CV of normal, osteopenia and osteoporosis were 1.26, 0.94, 0.94 g/cm2 in L-spine and 0.94, 0.79, 1.01 g/cm2 in femur. And the user_2’s %CV were 0.97, 0.83, 0.72 g/cm2 L-spine and 0.65, 0.65, 1.05 g/cm2 in femur. When analyzing the result, we figured out that the difference of reproducibility was almost not found but the differences of two users’ several result values have effect on total reproducibility. Conclusions: Precision test is a important factor of bone density follow up. When Machine and user’s reproducibility is getting better, it’s useful in clinics because of low range of deviation. Users have to check machine’s reproducibility before the test and keep the same mind doing BMD test for patient. In precision test, the difference of measured value is usually found for ROI change caused by patient position. In case of osteoporosis patient, there is difficult to make initial ROI accurately more than normal and osteopenia patient due to lack of bone recognition even though ROI is made automatically by computer software. However, initial ROI is very important and users have to make coherent ROI because we use ROI Copy function in a follow up. In this study, we performed precision test considering bone density condition and found LSC value was stayed within 3%. There was no considerable difference. Thus, patient selection could be done regardless of bone density condition.

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Precision DXA Bone mineral densitometry Least significant change