Gated Cardiac Blood Pool scan에서의 심장 주위 배후방사능 관심영역 설정시 산란선의 영향을 감소시키기 위한 연구

• 영문명: Study a Technique for Reducing the Influence of Scattered Rays from Surrounding Organs to the Heart during Gated Cardiac Blood Pool scan
• 발행기관: 대한핵의학기술학회
• 저자명: 김정열(Jung Yul Kim) 박훈희(Hoon Hee Park) 남궁혁(Hyuk Nam Koong) 조석원(Suk Won Cho) 김재삼(Jae Sam Kim) 이창호(Chang Ho Lee)
• 간행물 정보: 『핵의학기술』Vol.12 No.1, 33~38쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2008.05.30

영문 초록

Purpose: The Gated cardiac blood pool scan is non-invasive method that a quantitative evaluation of left ventricular function. Also this scan have shown the value of radionuclide ejection fraction measurements during the course of chemotherapy as a predictor of cardiac toxicity. Therefore a reliable method of monitoring its cardiotoxic effects is necessary. the purpose of this study is to minimize the overestimate of left ventricular ejection fraction (LVEF) by modified body position to reduce the influence of scattered rays from surrounding organs of the heart in the background region of interest. Materials and Methods: Gated cardiac blood pool scan using in vivo 99mTc-red blood cell (RBC) was carried out in 20 patients (mean 44.8±8.6 yr) with chemotherapy for a breast carcinoma. Data acquisition requires about 600 seconds and 24 frames of one heart cycle by the multigated acquisition mode, Synchronization deteriorates toward the end of the cycle and with the distance from the trigger signal (R-wave) by ECG gating. Gated cardiac blood pool scan was studied with conventional method (supine position and the detector head in 30-45° left anterior oblique position and caudal 10-20° tilt) and compared with modified method (left lateral flexion position with 360 mL of drinking water). LVEF analysis was performed by using the automatically computer mode. Results: The ROI counts of modified scan method were lower than LV conventional method (1429±251 versus 1853±243, <0.01). And LVEF of modified method was also decrease compared with conventional method (58.3±5.6% versus 65.3±6.1%, <0.01). Imaging analysis indicated that stomach was expanded because of water and spleen position was changed to lateral inferior compared with conventional method. Conclusion: This study shows that the modified method in MUGA reduce the influence of scattered rays from surrounding organs. Because after change the body position to left lateral flexion and drinking water, the location of spleen, left lobe of liver and stomach had changed and they could escaped from background ROI. Therefore, modified method could help to minimize the overestimate LVEF (%).

목차

서론

대상 및 방법

결과

고찰

결론

REFERENCES

키워드

Gated cardiac blood pool RBC LV EF ROI