Supernumerary Mediastinal Parathyroid Carcinoma Resulting in Recurrent Primary Hyperparathyroidism and Hypercalcemic Crisis: A Case Report

• 영문명: Supernumerary Mediastinal Parathyroid Carcinoma Resulting in Recurrent Primary Hyperparathyroidism and Hypercalcemic Crisis: A Case Report
• 발행기관: 대한내분비외과학회
• 저자명: Kyle Irvine Russell Murphy Dimitrios Coutsinos
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』23권4호, 123~126쪽, 전체 4쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2023.12.31

영문 초록

Primary hyperparathyroidism is a common cause of hypercalcemia but is rarely caused by a parathyroid carcinoma. Supernumerary glands are also uncommon in the setting of recurrent disease. We present a case of an 87-year-old female who presented in a hypercalcemic crisis due to recurrent primary hyperparathyroidism. Imaging studies showed a large parathyroid adenoma in the superior mediastinum believed to be a supernumerary gland. She was taken for a joint operation with ear, nose and throat and thoracic surgery where she underwent a thoracoscopic resection of the gland. The lesion appeared to be locally invasive involving the mediastinal fat and azygous vein. Intraoperative parathyroid hormone (PTH) levels showed an appropriate drop and post-operative calcium levels normalised. Final pathology showed a 5 cm parathyroid adenoma which in the setting of her significantly elevated PTH and locally aggressive lesion would be consistent with a supernumerary parathyroid carcinoma.

목차

INTRODUCTION

CASE REPORT

DISCUSSION

REFERENCES

키워드

Parathyroid carcinoma Thoracoscopic surgery