전신 발작으로 오인된 파킨슨병 환자에서의 이상운동증-고열증 증후군

• 영문명: Dyskinesia-Hyperpyrexia Syndrome in Patient with Parkinson’s Disease Mistaken for General Seizure
• 발행기관: 대한임상노인학회
• 저자명: 정다은(Dar-Eun Jung) 송인욱(In-Uk Song)
• 간행물 정보: 『대한임상노인학회지』제24권 제3호, 127~130쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2023.12.31

영문 초록

Dyskinesia-hyperpyrexia Syndrome (DHS) is a rare movement disorder emergency associated with Parkinson’s disease (PD), characterized by severe continuous dyskinesia accompanied by high fever and subsequent alterations in mental state. We present the case of a 74-year-old man with a nine-year history of PD who was admitted to the emergency room. He exhibited severe general dyskinesia, including myoclonus and chorea, along with a high fever and a stuporous mental state. Upon initial examination, a general myoclonic seizure associated with high fever was suspected. Consequently, the patient received hydration, antipyretic therapy, and sedative treatment. Upon the recovery of mental status, it was discovered that he had taken a higher dose of dopaminergic medication than usual on the day of his visit, as per his medical history. Subsequently, it was hypothesized that the severe dyskinesia, high fever, and loss of consciousness were related to this increased medication dosage. Therefore, his final diagnosis was DHS in PD. The dosage of dopaminergic medication was adjusted, and re-education was provided to the patient. This case report highlights the importance of recognizing DHS, as this patient was initially misinterpreted as having a generalized seizure due to severe dyskinesia and impaired mental state.

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키워드

Dyskinesias Hyperthermia Parkinson Disease Seizures