관심 영역 설정에 따른 Gates법 토리여과율의 유효성 평가

• 영문명: Evaluation of Validity Glomerular Filtration Rate Measured by Gates Method according Region of Interest
• 발행기관: 대한방사선과학회(구 대한방사선기술학회)
• 저자명: 박수영 안성민
• 간행물 정보: 『방사선기술과학』제46권 제5호, 417~425쪽, 전체 9쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2023.10.31

영문 초록

The glomerular filtration rate (GFR) has been the subject of much research as a key indicator for diagnosing, treating, and monitoring kidney function. The gamma camera method (Gates method) is simple and allows simultaneous acquisition of GFR and renal scintigraphy for each kidney, however its accuracy is inferior. This study aimed to inves-tigate changes in GFR depending on how region of interest (ROI) are set up, which is one of many factors influencing accuracy. GFR was calculated by setting the ROI for each phase of the image acquisition time (Gates-1: 0∼1 minutes, Gates-2: 1∼3 minutes, Gates-3: 3∼27 minutes), and statistical significance was verified based on probability value 0.05 through ANOVA analysis. While there was no statistically significant difference among results from Gates-1, 2, 3 (p=0.481>0.05), overall results from the Gates method tended to overestimate compared to those from the multiple blood sampling-dual ex-ponential (MBSDE) method. When comparing averages between phases, results from Gates-2 were most similar to those from the MBSDE method. Moreover, paired t-test p-values between MBSDE method and phases were as follows Gates-1: 0.021 (p<0.05), Gates-2: 0.280 (p>0.05), and Gates-3: 0.164 (p>0.05) indicating that only Gates-1 had statistically sig-nificant differences compared with MBSDE method. Thus, setting ROI around 2∼3 minutes is calculated can aid in accu-rately determining GFR when Gates Method.

목차

Ⅰ. 서 론

Ⅱ. 대상 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

REFERENCES

키워드

토리여과율 다중채혈 이중 지수 법 감마카메라 Gates 법 관심 영역 Glomerular Filtration Rate (GFR) Multiple Blood Sampling-Dual Exponential Method (MBSDE) Gamma Camera Gates Method Region Of Interest (ROI)