설포라판과 라스베라트롤의 병용투여가 흰 쥐의 안면부 통증조절에 미치는 영향

• 영문명: Effects of Combined Administration of Sulforaphane and Resveratrol on Orofacial Pain Control in Rats
• 발행기관: 한국구강보건과학회
• 저자명: 박민경 천세희 김경민 김혜진 이민경
• 간행물 정보: 『한국구강보건과학회지』제11권 제3호, 114~119쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2023.09.30

영문 초록

Objectives: This study was designed to confirm the effects of natural products on the control of facial pain. Methods: In this study, 5% formalin was injected into the face of the experimental animals to induce pain behavioral responses, and sulforaphane 15 μg or 150 μg/50 μl and resveratrol 20 μg or 200 μg/50 μl were pre-treated to confirm the pain control effects. Results: The two drugs showed pain-modifying effects in a concentration-dependent manner. In addition, a significant analgesic effect was confirmed when the two drugs were co-administered at low concentrations. Conclusions: Therefore, through this experiment, sulforaphane and resveratrol can be effective therapeutic agents for controlling orofacial pain.

목차

Ⅰ. 서론

Ⅱ. 연구방법

Ⅲ. 결과

Ⅳ. 고찰

Ⅴ. 결론

REFERENCES

키워드

Combined administration Orofacial pain Sulforaphane Rat Resveratrol