두경부암에서 정밀의료

• 영문명: Precision Medicine in Head and Neck Cancer
• 발행기관: 대한두경부종양학회
• 저자명: 박혜성 강진형
• 간행물 정보: 『대한두경부종양학회지』제39권 제1호, 1~9쪽, 전체 9쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2023.05.31

영문 초록

Technological advancement in human genome analysis and ICT (information & communication technologies) brought ‘precision medicine’ into our clinical practice. Precision medicine is a novel medical approach that provides personalized treatments tailored to each individual by precisely segmenting patient populations, based on robust data including a person’s genetic information, disease information, lifestyle information, etc. Precision medicine has a potential to be applied to treating a range of tumors, in addition to non-small cell lung cancer, in which precision oncology has been actively practiced. In this article, we are reviewing precision medicine in head and neck cancer (HNC) with focus on tumor agnostic biomarkers and treatments such as NTRK, MSI-H/dMMR, TMB-H and BRAF V600E, all of which were recently approved by U.S. Food and Drug Administration (FDA).

목차

배경

두경부암의 역학과 병인

두경부암의 치료

정밀의료와 두경부암

결론

References

키워드

Head and neck cancer (HNC) Next generation sequencing (NGS) Personalized therapy Precision medicine Targeted therapy