Inhibitory effect of Taemyeongcheong on allergic reactions

• 발행기관: 셀메드 세포교정의약학회
• 저자명: Ka-Jung Ryu Myeong-Sook Yoou Kun-Young Park
• 간행물 정보: 『셀메드』Volume 6 Issue 2, 1~5쪽, 전체 5쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2016.05.31

영문 초록

Taemyeongcheong (TMC) is Korean traditional extracted drink with various health ingredients. TMC has been used to treat hepatic damage, obesity, gastritis, and colitis. However, the role of TMC on allergic reaction has not been studied yet. In this study, we investigated the anti-allergic effects of TMC against a compound 48/80-induced systemic anaphylactic reaction and IgE-mediated passive cutaneous anaphylaxis (PCA). TMC significantly inhibited the compound 48/80-induced systemic anaphylactic reaction and IgE-mediated PCA reaction. Furthermore, TMC reduced the levels of interleukin (IL)-ip, IL- 4, IL-13, and vascular endothelial growth factor in the serum of mice under PCA reaction. Taken together, these results suggest that TMC can play a useful role as an anti-allergic agent.

키워드

Taemyeongcheong systemic anaphylactic reaction passive cutaneous anaphylaxis cytokines