살아있는 미생물의 최신 장내 전달 기술에 대한 고찰

• 영문명: Intestinal Delivery Techniques for Live Microorganisms: A Brief Overview
• 발행기관: 대한약학회
• 저자명: 김지현 쉐이 퓨 랑이(Shwe Phyu Hlaing) 이주호 사파르바예바 아루잔(Aruzhan Saparbayeva) 유진욱
• 간행물 정보: 『약학회지』제66권 제4호(2022년), 184~191쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2022.08.30

영문 초록

The gut microbiome is a critical determinant of human health and disease status. Administration of live microorganisms has emerged as an effective way to recover damaged gut microbiome for improving host health. However, live microorganisms are susceptible to various environmental stresses, including acidic pH during the gastric transit. Thus, appropriate delivery techniques are required to protect the live microorganisms during their transit to the target area and ensure their release at a desired location such as ileum or ascending colon. In this review, we provide an overview of intestinal delivery techniques for live microorganisms.

목차

서 론(Introduction)

결 론(Conclusion)

References

키워드

Live microorganisms Probiotics Live biotherapeutic products Gastric survival Intestinal delivery