Medical genomic approach to early-onset scoliosis

• 발행기관: 대한의학유전학회
• 저자명: Shin-Young Yim
• 간행물 정보: 『대한의학유전학회지』제18권 제2호, 94~100쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2021.12.31

영문 초록

Early onset scoliosis (EOS) describes the onset of scoliosis before the age of 10 years and is associated with significant health risks. Compared to adolescent idiopathic scoliosis, studies on the etiology of EOS in children are more common. EOS in-cludes inhomogeneous groups of patients, and the etiology of EOS may be congenital, neuromuscular, syndromic, or idio-pathic. The identification of the molecular etiology underlying patients with EOS has been increasing. This could provide valuable information for optimizing the management and care of these children. In this review, EOS was reviewed from a medical genomic perspective.

목차

Introduction

Congenital Scoliosis

T-box Transcription Factor 6-associated Con-genital Scolios

EOS in Syndromes

EOS in Neuromuscular Diseases

Conclusion

References

키워드

Scoliosis Child Genomics