기능성 소화불량의 기능의학적 접근과 관리

• 영문명: Approach and management of functional dyspepsia in functional medicine
• 발행기관: 대한기능의학회
• 저자명: 이상훈(Sang-Hoon Lee) 김상만(Sang Man Kim)
• 간행물 정보: 『Journal of Korean Institute for Functional Medicine』Vol.4 No. 2, 1~11쪽, 전체 11쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2021.11.30

영문 초록

Functional dyspepsia (FD) is defined as the presence of one or more of the following symptoms, postprandial fullness, early satiation, epigastric pain or burning sensation, with no evidence of structural disease to explain the symptoms. The prevalence of FD ranges from 5 to 11 percent worldwide. The pathophysiology of FD is not well elucidated and the management of patients with FD is still controversial, so the current treatment can improve the symptoms in only a small proportion of patients. In addition, the role of Helicobacter pylori (H. pylori) infection in FD has been emphasized. Although the mechanism remains uncertain, eradication of H. pylori is associated with a small but significant benefit in alleviating symptoms. The standard treatment of H. pylori is multiple antibiotics therapy. Its cure rate is up to 70 to 80%. But adverse drug effects such as nausea, epigastric pain, indigestion and diarrhea are reported about 50% of patients, and the drug discontinuation rate is also reported up to 10%. However, alternative treatment options have not been established yet. Therefore, the authors will review the functional medicine approach and nutritional therapy of FD and H. pylori infection, and suggest future research directions.

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키워드

Functionalmedicine Dyspepsia Helicobacterpylori Nutritiontherapy