키토산의 분자량에 따른 랫드에서의 적용

• 영문명: Application of Rats According to Molecular Weight of Chitosan
• 발행기관: 한국환경보건학회
• 저자명: 정덕채(Jung, Duck-Chae) 이기창(Lee, Ki-Chang) 윤철훈(Yoon, Cheol-Hun) 김판기(Kim, Pan-Gyi) 신동환(Shin, Dong-Hwan)
• 간행물 정보: 『한국환경보건학회지』제25권 제3호, 58~63쪽, 전체 6쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 1999.09.30

영문 초록

Biodegradable films were prepared by solution blend method in the weight ratio of chitosan for the purpose of useful biomaterials. The possibility of biomaterials prepared from natural polymer as a skin substitute was evaluated by measuring biocompatibility. These films were inserts in the back of rat and their biodegradability was investigated by the film weight and hematology as a function of time for the biotransformation. The result of rat test showed that medium, high viscosity chitosan induced some suspects of inbiocompatibility in the tissue by goreign body reaction 48 and 72 hours after implantation. Also, we prepared the official burn ointment which is made by low viscosity chitosan. This burn ointment was covered on the skin wound of artificial burn and their effect of healing was investigated by the evaluation of the naked eye and hematological change as a function of time. The result of rats test showed that burn ointments made from chitosan was effective reductio of inflammation than negative group.

목차

Ⅰ. 서론

Ⅱ. 실험방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

참고문헌

키워드

Chitosan Biodegradation Insertion Skin implants Burn ointments