눈꺼풀속말림, 두줄속눈썹 환자에서 시축을 침범한 양안 각막 아밀로이드증

• 영문명: Bilateral Corneal Amyloidosis Extended into Visual Axis Secondary to Entropion and Distichiasis
• 발행기관: 대한검안학회
• 저자명: 노성래(Sung Rae Noh) 양찬민(Chan Min Yang) 김태기(Tae Gi Kim) 진경현(Kyung Hyun Jin)
• 간행물 정보: 『Annals of optometry and contact lens』Vol.16 No.2, 79~82쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2017.06.30

영문 초록

Purpose: To report a rare case of bilateral secondary corneal amyloidosis with visual disturbance secondary to entropion and distichiasis. Case summary: A 41-year-old man was referred to our clinic for the evaluation of decreased visual acuity in both eyes. Upon admission, the patient’s best-corrected visual acuity was 0.6 OD and count finger OS. External evaluation revealed entropion in both lower eyelids as well as distichiasis involving all 4 eyelids cause irritation to cornea. Slit-lamp examination revealed corneal opacity in the right peripheral cornea and left center cornea. The appearance of corneal opacity is gray-whitish circle with diameter 5 mm in right and 4 mm in left, also presented with gelatinous irregular surface and neovascularization in the right eye. Penetrating keratoplasty was performed for decreased visual acuity in the left eye. Histopathologic analysis of corneal button revealed deposition of amorphous, eosinophilic material just beneath the corneal epithelium. These opacities stained with Congo red and demonstrated apple green birefringence and dichroism. Secondary localized amyloidosis of the cornea was diagnosed without any systemic involvement. Entropion repair and hyfrecation was performed 1 month after penetrating keratoplasty. By the 4 years after penetrating keratoplasty, the patient’s best-corrected visual acuity was 0.9 OD and the patient showed no evidence of corneal graft rejection and recurrence of amyloidosis. Conclusion: Irritation by eyelashes can cause corneal opacity and amyloidosis in patients with distichiasis or entropion.

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키워드

Corneal amyloidosis Distichiasis Entropion Penetrating keratoplasty