Rubus속 식물에 존재하는 19alpha−Hydroxyursane−type Triterpenoid의 특성과 이용

• 영문명: Chemical Characterization and Utilization of 19alpha−Hydroxyursane−type Triterpenoids in Rubus species
• 발행기관: 한국자원식물학회
• 저자명: 정현주 남정환 임상철 김원배 박희준
• 간행물 정보: 『한국자원식물학회지』제19권 제5호, 563~572쪽, 전체 10쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2006.10.30

영문 초록

The plant Rubus species (Rosaceae) mainly contains 19α−hydroxyurane−type triterpenoids (19α−HUT) as bioactive components. Available functional food includes blackberry (the fruit of thornless Rubus sp.), red raspberry (R. idaeus) and black raspberry (R. occidentalis). However, the fruit of R. coreanus, which is used in Korea as a functional food, substitutes black raspberry. Rubi Fructus, which has been traditionally used as an oriental medicinal drug, designates only unripe fruit of R. coreanus but not its ripe fruit which indicates that it needs high content of 19α−HUT as a crude drug. Throughout our experiment, we found that ripe fruits contain very little amount of 19α−HUT when compared to unripe fruits. In addition, various and rich 19α−HUT has been reported from Rubus species. The most common structure of 19α−HUT of Rubus species, euscaphic acid or tormentic acid with 3α−OH or 3β−OH, respectively, can be glycosylated or oxidized to produce a number of 19α−HUTsas euscaphic acid and tormentic acid derivatives and even esterified to form dimeric triterpenoids. In this review, the bioactivity and biosynthetic pathway and chemical characterization of 19α−HUTs found in Rubus species are discussed.

키워드

Rubus Rosaceae Triterpenoid Blackberry 19α− hydroxyurane− type Tormentic acid Euscaphic acid