Screening for Anti-diabetic Effects of Prescribed Korean Traditional Medicines

• 발행기관: 한국자원식물학회
• 저자명: Seon Mi Shin Yong Joon Jeong Dae Won Park Heung Ko Gi tae Kim Ee-Hwa Kim Taeseong Kim Eun-Hwa Sohn Jung-Eun Kwon Hyun Jung Koo Se Chan Kang
• 간행물 정보: 『한국자원식물학회지』제25권 제6호, 670~681쪽, 전체 12쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2012.12.30

영문 초록

Herb extracts commercially used in Korea were screened for PPAR-γ agonist test and α-glucosidase inhibition assay. Total 16 herb plants had a PPAR-γ agonist activity. Specially, Alisma orientale Juz (108.41%), Ephedra sinica (98.22%), Sasa japonica Makino var. purpurascens Nakai (140.68%), Astragalus membranaceus Bunge (106.79%) and Cnidium officinale Makino (113.00%) showed high PPAR-γ agonist activity rate compared with rosiglitazone’s (167.46%). And Cornus officinalis S. et Z. (90.3%), Cinnamomum cassia Blume (89.2%), Psoralea corylifolia L. (89.8%), Paeonia japonica (Makino) Miyabe (92.4%) and Paeonia suffruticosa Andr (93.2%), showed high α-glucosidase inhibition rates. These results support previous reports of the efficacy of Oriental medicinal plants used for diabetes mellitus.

목차

Introduction

Materials and Methods

Results and Discussion

Acknowledgment

Literature Cited

키워드

Korean traditional medicine Screening PPAR-γ agonist α-Glucosidase inhibition Diabetes mellitus