Resveratrol과 관련 유도체 합성 및 효능에 관한 고찰

• 영문명: Review on the Synthesis and Biological Activities of Resveratrol and Its Derivatives
• 발행기관: 대한약학회
• 저자명: 김초롱(Cho-rong Kim) 이상협(Sang Hyup Lee)
• 간행물 정보: 『약학회지』제64권 제5호(2020년), 343~349쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2020.10.30

영문 초록

Resveratrol, a type of phytoalexin found in many plants, is known to be a useful component for human health. It is found in vegetables, fruits, wines and teas, and especially in grapes. Resveratrol has been reported to have various medicinal effects, such as anti-inflammatory, anti-cancer and anti-aging effects. In particular, anti-cancer effects are believed to be achieved by suppressing the growth of cancer cells and therefore, decreasing cancer organisms. Based on this usefulness, extensive efforts to synthesize resveratrol have been continued. Some of the typical methods using Heck reaction, Perkin reaction and Wittig reaction have been reported, and further studies for improvement are still in progress. Derivative syntheses by substituting hydroxy groups of resveratrol with alkyl or halogen groups were also performed along with investigation of biological properties of the related compounds. As a result, synthesis and biological evaluation of resveratrol and its derivatives were discussed to assess and enhance the potential of resveratrol as a medicinal component and/or a dietary supplement.

목차

서 론(Introduction)

결 론(Conclusion)

References

키워드

Resveratrol polyphenol trihydroxystilbene antioxidant anticancer