LPS로 염증이 유도된 RAW 264.7 대식세포에 대한 B 약침액의 항염증 효과

• 영문명: Anti-inflammatory Activity of B Yakchim Fluid on the LPS-stimulated RAW 264.7 Macrophages
• 발행기관: 임상약침학회
• 저자명: 이경진(Kyung-Jin Lee) 정철(Chul Jung) 김학주(Hak-Ju Kim)
• 간행물 정보: 『임상약침학회학회지』대한면역약침학회지 제3권 제2호, 1~8쪽, 전체 8쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2014.12.30

영문 초록

Objectives : The purpose of this study was to investigate the anti-inflammatory activities of B Yackchim fluid. Methods : The total sugar, total reducing sugar, and protein contents in B Yackchim fluid were analyzed. To investigate the anti-inflammatory effects of B Yackchim fluid, nitric oxide (NO), interleukin-2 (IL-2), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in the LPS-stimulated RAW 264.7 macrophage were measured. Results : B Yackchim fluid consists of 0.12 mg/ml of total sugar, 0.08 mg/ml of total reducing sugar. However, total protein was not detected. B Yackchim fluid showed anti-inflammatory effects by reducing the production of NO, IL-2, IL-6, and TNF-α. However, B Yackchim fluid showed cell cytotoxicity. Conclusions : B Yackchim fluid might have anti-inflammatory effects. However, more studies including efficacy and safety should be needed to use anti-inflammatory agent in Korean medicine.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 결 과

Ⅳ. 고찰 및 결론

참고문헌

키워드

B Yackchim Anti-inflammatory effect Nitric oxide Interleukin-2 Interleukin-6 Tumor necrosis factor-α