Intraocular Infusate with Hemocoagulase for the Control of Bleeding during Vitreous Surgery

• 발행기관: 대한안과학회
• 저자명: Ho Sung Lee Sang Ha Kim In Taek Kim
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.3 No.1, 6~10쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1989.06.30

영문 초록

The effects of hemocoagulase in injectable form (hemocoagulating enzymatic fraction of South American snake Bothrops jararaca venom provided by Ravizza) on the control of intraocular bleeding during vitreous surgery were evaluated in rabbit eyes. Intraocular infusion solution with hemocoagulase (1 NIH thrombin unit/100 ml of BSS plus) significantly reduced the bleeding time. Electroretinogram b-wave and electroretinogram c-wave showed no abnormality. Infusate with hemocoagulase (1 NIH thrombin unit/100 ml of BSS plus) is not toxic to retinal tissue and appeared to be a useful agent for the control of intraocular bleeding during vitreous surgery.

목차

Abstract

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

키워드

hemocoagulase bleeding time vitrectomy retinal toxicity