抗콕시듐劑 抗生物質의 닭 體內代謝 및 殘留에 關한 硏究

• 영문명: Studies on pharmacokinetics and residues of polyether antibiotics in chicken
• 발행기관: 한국예방수의학회
• 저자명: Tae Haeng Cho(趙太行) Kwang Jick Lee(李光稙) Sun Namgoong(南宮琁) Jong Myung Park(朴鍾鳴) Mun Han Lee(李文漢)
• 간행물 정보: 『Korean Journal of Veterinary Public Health』Vol.17, No.3, 329~338쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1993.12.30

영문 초록

Detection for residues of polyether antibiotics(Salinomycin, Monensin, Lasalocid and Naracin) in chicken tissues-kidney, fat, liver and muscle was performed by the TLC and bioautography. B. subtillis ATCC 6633 strain, ethyl acetate and chlorform : methanol : conc. NH₄OH(95/5/0.5) solvent and addition of MgCl₂ in media were used in these experiments. Eighty chickens were divided four groups : 2 normal level feeder groups (monensin 110ppm, salinomycin 50ppm), 2 high level feeder groups(monensin 550ppm, salinomycin 250ppm) for five weeks. The recovery rate of monensin, salinomycin, lasalocid and naracin was 85.9~100.5%, 88.8%, 86.8% and 87.8% in chicken tissues at each. In high level feeder groups, monensin and salinomycin were detected about 0.052ppm and 0.085ppm at each in fat tissue at 24hours after feeding The duration of residues in high level feeder groups lasted longer than that of normal level feeder groups. Besides this test we have performed the amount of contamination of polyether antibiotics in twenty market chickens, so there is no residue of polyether antibiotics in the chiken tissue.

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參考文獻

키워드

Anticoccidant Chicken Pharmacokinetic Residue