Permeation characteristics of thermal paper ingredients using Franz diffusion cell

• 발행기관: 한국예방수의학회
• 저자명: Kyo-Hyun Park Se-Hoon Jung Ho-Sang Shin Seong-Eun Lee Kiyoung Lee Bae-Hwan Kim
• 간행물 정보: 『Journal of Preventive Veterinary Medicine』Vol.40, No.1, 30~34쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2016.03.30

영문 초록

The purpose of this study is to examine the exposure risk of thermal paper ingredients by analyzing skin permeation using an in vitro Franz cell. Thermal printer papers are usually used for receipt papers, and the skin of shop assistant is continuously exposed to hazardous ingredients of thermal papers. The skin permeation risk of thermal paper ingredients, including bisphenol A and toluene, was determined using an in vitro Franz diffusion cell method using hairless mouse full skin and human cadaver epidermis. Bisphenol A, a major component in each thermal paper, showed moderate skin penetration. Most skin absorption rates were similar in both hairless mouse full skin and human cadaver epidermis. The possible risk of exposure to toxic substances in thermal paper was confirmed from this study. These is results are expected to contribute to establishment of management regulations for thermal papers.

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키워드

Thermal paper skin permeation franz diffusion cell exposure risk