알코올 의존 환자의 혈장 5-Hydroxyindoleacetic Acid 농도와 공격성에 관한 연구

• 영문명: The Plasma 5-Hydroxyindoleacetic Acid Concentration and Aggression in Alcoholic Patient
• 발행기관: 한국중독정신의학회
• 저자명: 최은주(Eun-Ju Choi) 정혜경(Hae-Gyung Chung) 김규현(Kyu-Hyun Kim) 정문용(Moon-Yong Chung) 이명희(Myoung-Hee Lee)
• 간행물 정보: 『중독정신의학』Vol.4, No.2, 123~130쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2000.09.30

영문 초록

The purpose of this study was to investigate the difference between alcoholic patients and normal controls on plasma 5-hydroxyindoleacetic acid (5-HIAA) concentration, aggression, and their correlation. We compared 40 alcoholic patients who were admitted to Korea Veterans Hospital and Chunchon National Mental Hospital with 30 controls. All subjects were assessed by plasma 5-HIAA concentration, National Mental Hospital Alcoholism Screening Test, State-Trait Anger Expression Inventory. Results were as follows：1) Alcoholic patients’ plasma 5-HIAA level was significantly lower than controls. Scores of state anger, trait anger, and angerout in alcoholic group were significantly higher than controls. 2) There was no statistically significant correlation between plasma 5-HIAA level and aggression in alcoholic patients. Conclusively, we suggest that alcohol has a significant effect on both serotonin turnover and aggressive behavioral problems. But we cannot find correlation with plasma 5-HIAA level and aggression in Korean alcoholics. Further studies, specific and appropriate assessment and its treatment are needed for alcoholic patients.

키워드

Alcoholic patient Plasma 5-HIAA Aggression