Carbamate 화합물의 합성 및 위생학적 연구

• 영문명: Synthesis and Biological Activities of Carbamate Derivative
• 발행기관: 한국환경보건학회
• 저자명: 강회양
• 간행물 정보: 『한국환경보건학회지』제22권 제2호, 19~24쪽, 전체 6쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 1996.06.30

영문 초록

Carbamates are generally used as insecticide, thus 5.7-dichloro-8~hydroxyquinolinyl- N-ethylcarbamate was newly synthesized. Its physical properties were determined and chemical structure was identified by means of I.R., nmr in addition to elemental analysis. The yield of addition, using triethylamine as catalyst, 5.7-dichloro-8-hydroxyquinoline and isocyanate was better than that of condensation of 5.7-dichloro-8-hydroxyquinoline with carbamoylchloride. The effct of the compound on rabbit s ileum, and antibacterial activity against Staphylococcus aureus, Salmonella typhi, Echerichia coli, and Pseudomonas aeruginosa were examined. The present organic synthesized compound showed the bacteriostatic action on salmonella typhi, escherichia coli, and pseudomonas aeruginosa, but no otherwise effect of contraction of rabbit s ileum in the concentration of $250 \mu g/ml$.

키워드

5.7-dichloro-8-hydroxypuinoliny1-N-ethylcarbamate antibacterial activity 5.7-dichloro-8-hydroxyquinoline bacteriostatic action insecticide