성견의 골결손부에서 3종의 지혈제가 골재생에 미치는 영향

• 영문명: Effects of hemostatic agents on osseous regeneration
• 발행기관: 대한구강악안면외과학회
• 저자명: 김영운(Young Woon Kim) 류선열(Sun Youl Ryu) 최홍란(Hong Ran Choi)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제22권 제1호, 101~111쪽, 전체 11쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 1996.01.30

영문 초록

This study was done to evaluate the effects of commonly-used hemostatic agents on bone regeneration Histopathological and radiographical examinations were done to determine the degree of bone healing. The dogs weighing average of 15kg, were used, and four surgical defects sized 1×1×1cm were created at the iliac crest. Surgicel, Amicar and Beriplast were placed in each three surgical defects. The animals were sacrificed at 2, 4, 6 and 8 weeks after operation. Results obtained were as follows: 1. At 2 weeks, every operation site showed a radiopacity only slightly less than that of normal unaffected bone, and the site that contained Amicar had lowest radiopacity among the experimental groups. 2. At 4-8 weeks, radiopacity in every experimental group was similar to that of normal bone. 3. At 2 weeks, there was no evidence of remnant hemostatic agents through the absorption process in histopathological finding. 4. At 4-8 weeks, there was no difference in histopathological finding among the groups. Bone healing was good in every experimental group. In Beriplast group, bone healing was slightly faster than others. These results suggest that three hemostatic agents have no differnece in affecting the progression of healing the bony defects when compare to control group.

목차

Abstract

I. 서론

II. 재료 및 방법

III. 성적

IV. 고찰

V. 결론

참고문헌

키워드

Hemostatic agents Osseous regeneration