구강편평세포암종 이식 누드마우스에서의 혈액 점도 변화

• 영문명: BLOOD VISCOSITY CHANGE IN ORAL SQUAMOUS CELL CARCINOMA XENOTRANSPLANTED NUDE MICE
• 발행기관: 대한구강악안면외과학회
• 저자명: 명훈(Hoon Myoung) 이종호(Jong-Ho Lee) 정필훈(Pill-Hoon Choung) 김명진(Myung-Jin Kim)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제30권 제2호, 81~84쪽, 전체 4쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2004.04.30

영문 초록

It is well known that malignant tumor have hypoxic cell fraction, which is radio resistant and is one of the most important cause of local recurrence after radiotherapy. One of the causes of hypoxia in tumor is blood flow decrease due to increase in blood flow resistance and one of the causes of increased blood flow resistance could be attributed to the increase in blood viscosity. For the evaluation of the change of blood viscosity in oral cancer, experiments were carried out to test the change of blood viscosity among the normal control and xenografted oral cancer nude mice. Relative viscosity measured against distilled water was 3.30±0.14 for normal control, and 3.67±0.62 for tumor bearing mice at the first time of blood sampling in experimental period (100 mm3 0.05). However, as the tumor grew, significant difference of blood viscosity was detected at the third time of blood sampling (control group:3.37±0.59, and experimental group: 4.31±0.41 300 mm3

목차

키워드

Oral cancer Blood viscosity

참고문헌