Collagen biology for bone regenerative surgery

• 영문명: Collagen biology for bone regenerative surgery
• 발행기관: 대한구강악안면외과학회
• 저자명: Masaru Murata
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제38권 제6호, 321~325쪽, 전체 5쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2012.12.30

영문 초록

Collagen is widely used for regenerative therapy and pharmaceutical applications as one of the most useful scaffolds. Collagen is the most abundant protein in vertebrates and the natural substrate of various types of animal cells. Bone and dentin are mineralized tissues and almost similar in chemical components. They consist of collagen (18%), non-collagenous proteins (2%), hydroxyapatite (70%) and body fluid (10%) in weight volume. Pepsindigested, type I collagen (atelocollagen) and heat-denatured collagen (gelatin) are basic collagenous materials for medical use. Demineralized dentin matrix (DDM) and demineralized bone matrix (DBM) belong to acid-insoluble group, and vital tooth-derived DDM is a unique dentin material including cementum and growth factors. In this review, collagen-based materials will be introduced and discussed for bone regenerative surgery.

목차

I. Introduction

I. Introduction

III. Collagen

IV. Collagenous Biomaterials

V. BMPs

VI. Autograft of Bone and Dentin

VII. Conclusion

키워드

Collagen Biomaterial Dentin Bone Regeneration