원격 전이로 재발한 갑상선 유두암에 대한 임상적 고찰

• 영문명: Clinical Manifestations of Papillary Thyroid Carcinoma Recurred as Distant Metastases
• 발행기관: 대한두경부종양학회
• 저자명: 김남영(Nam Young Kim) 김경헌(Kyoung Hun Kim) 박성호(Sung Ho Park) 이국행(Guk Haeng Lee) 이병철(Byeong Cheol Lee) 이명철(Myung-Chul Lee) 최익준(Ik Joon Choi)
• 간행물 정보: 『대한두경부종양학회지』제31권 제2호, 11~15쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2015.11.30

영문 초록

Background and Objectives: This study aimed to analyze the features of patients with papillary thyroid carcinoma (PTC) recurred as distant metastases (DM). Materials and Method: We retrospectively reviewed and analyzed clinical records of 63 patients who were treated for PTC recurred as DM between 2000 and 2006. Univariate and multivariate analyses of various clinical factors were performed. Results: Male patients were 12, and female patients were 51. The 5- and 10-year survival rates for PTC recurred as DM were 85% and 73%, respectively. Size of tumor, multi-plicity of tumor, lateral neck node metastasis, and RAI ablation therapy with other treatments such as surgery were associated with survival rate (p < 0.005) in univariate analysis. The lateral neck node metastasis[p =0.039, hazard ratio=2.2(95% CI. 1.18~3.24)] and multiple organ DM[p =0.041, hazard ratio=2.18(95% CI. 1.03~2.89)] were related to the survival in multivariate analysis. Conclusion: PTC recurred as DM is uncommon (2.2%). The size of tumor, the multiplicity of tumor, lateral neck node metastasis and RAI ablation therapy with other treatments for DM were revealed as associated factors for the survival. Evaluation of DM should be considered in patients with PTC during long-term follow-up.

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키워드

Thyroid Papillary Carcinoma Distant Metastases 갑상선 유두암 원격 전이.