이하선 종양에서 세침흡인검사의 유용성

• 영문명: Efficacy of Fine Needle Aspiration Biopsy in Parotid Gland Tumors
• 발행기관: 대한두경부종양학회
• 저자명: 이창희(Chang Hee Lee) 이현섭(Hyun Sub Lee) 진성민(Sung Min Jin):이상혁(Sang Hyuk Lee) 표정수(Jung-Soo Pyo) 손진희(Jin Hee Sohn)
• 간행물 정보: 『대한두경부종양학회지』제27권 제2호, 204~209쪽, 전체 6쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2011.11.30

영문 초록

Background and Objectives：The usefulness of fine needle aspiration biopsy(FNAB) for diagnosis of parotid gland tumors is controversial, because of the generalized belief requiring surgery for most parotid tumors. The aim of this study was to evaluate the efficacy of FNAB for diagnosis in parotid gland tumors. Material and Methods：FNAB was performed in 91 patients who underwent parotid surgery at Kangbuk Samsung Hospital from January 2007 to December 2010. The result of FNAB, 11 malignancies and 75 benign tumors and 5 non-neoplasms were analyzed and compared with the final histopathologic diagnoses. Sensitivity, specificity, accu-racy, positive predictive value(PPV), and negative predictive value(NPV) were calculated using final histopatho-logic diagnosis of the surgical specimen as the standard diagnostic reference for comparative analysis. Results： 86 specimens(94.5%) were suitable for evaluation. We compared the result of FNAB and the final histopathology in 79(89.4%) cases. The sensitivity, specificity, accuracy, PPV, and NPV of FNAB for detecting pleomorphic adenoma was 95.8%, 88.4%, 92.3%, 90.2%, and 95.0%. In Warthin’s tumor, results were 86.4%, 94.2%, 92.3%, 82.6%, and 95.6%. Among 11 patients who were diagnosed with malignancy on final histopathologic report, only 3(30%) patients were diagnosed with the same as on FNAB, the other 8 patients were initially diagnosed incor-rectly as benign tumors in FNAB. There were no complications related to FNAB. Conclusion：Diagnostic accu-racy for FNAB in benign parotid tumors was high. However, in malignant tumors, FNAB shows low diagnostic usefulness compared with benign tumors. FNAB can be effective and safe diagnostic technique for evaluating the benign parotid glands tumors.

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Parotid neoplasm Fine-needle aspiration Diagnosis 이하선 종양 세침흡인검사 진단