전호(Anthriscus sylvestris) 뿌리 정유의 항균 및 항산화 작용

• 영문명: Antibacterial and Antioxidant Activities of the Essential Oil from the Roots of Anthriscus sylvestris
• 발행기관: 대한약학회
• 저자명: 임혜림(Hyerim Lim) 신승원(Seungwon Shin)
• 간행물 정보: 『약학회지』제56권 제5호 (2012년), 320~325쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.10.31

영문 초록

To develop a new effective and safe natural antibiotics and antioxidant the essential oil was extracted from the roots of Anthriscus sylvestris by steam distillation. Its composition was analyzed by GC-MS. The activities of the essential oil fraction and its main components were evaluated against antibiotic-susceptible and -resistant strains of some food-born bacteria. In addition the synergism was examined with this oil combined with antibiotic by checkerboard titer test. The antioxidant activities were determined by in 1,1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging activity test and reducing power assay. The essential oil fraction of A. sylvestris revealed significant inhibiting activities against antibiotic-susceptible and -resistant species of Vibrio and Shigella with MICs ranged from 1.00~4.00 mg/ml. It showed synergistic or additive effects when it was combined with amphicillin or trimethoprim/sulfamethoxazole (1 : 9). Additionally, the essential oil fraction of A. sylvestris exhibited significant DPPH free radical scavenging activity and the reducing power.

키워드

essential oil Anthriscus sylvestris myristicin antibacterial Shigella Vibrio anti-oxidant