들쭉 추출물의 노인성 황반변성증 예방 효과

• 영문명: Protective Effect of Vaccinium uliginosum L. Extract on Age-related Macular Degeneration
• 발행기관: 대한약학회
• 저자명: 김선미(Sun Mi Kim) 김혜주(Hye Ju Kim) 손미원(Miwon Son) 정세영(Se Young Choung)
• 간행물 정보: 『약학회지』제56권 제5호 (2012년), 314~319쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.10.31

영문 초록

Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among the elderly. In this study, extract of Vaccinium uliginosum L. that has potent antioxidant activity was evaluated as effective preventive supplement for AMD using AMD animal model induced by high fat diet and UV A irradiation. Treatment with VU extract protected photoreceptor cells of retina and blocked the accumulation of lipofuscin pigment-granules induced by high fat diet and UV A light irradiation. This study suggests that VU extract may be a useful agent for prevention of progress of AMD.

키워드

Vaccinium uliginosum L Age-related macular degeneration lipofuscin