라벤더향 흡입 후 치매환자의 혈장 중 신경전달물질의 농도변화

• 영문명: The Change of Plasma Neurotransmitters Concentration after Aromatherapy in Dementia Patients
• 발행기관: 대한약학회
• 저자명: 이경복(Kyung-Bok Lee) 강영숙(Young-Sook Kang)
• 간행물 정보: 『약학회지』제56권 제2호 (2012년), 86~91쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.04.30

영문 초록

The objective of this study is to examine how different concentration of neurotransmitters in plasma between patients with dementia and normal people regarding the inhalation of lavender oil. This study subjects were 9 elderly patients with dementia who live in nursing home and 9 normal women. Before and after inhalation, they were collected blood sample. Norepinephrine (NE), serotonin (5-HT), dopamine (DA), and r-aminobutyric acid (GABA) concentration analysis were performed. Before inhalation, dementia patients were significantly different with the normal group in GABA and DA, NE. Following inhalation in experimental group, dementia patients and normal group were only significantly increased in 5-HT. But it did not significantly change in the other neurotransmitters. After inhalation, dementia patients were significantly different with the normal group in GABA and 5-HT. This result suggests that the increase of 5-HT release by the inhalation of lavender oil related to reduce the behavioral and psychological symptoms of dementia.

키워드

lavender oil neurotransmitters aroma inhalation dementia patients