설페라존을 사용하여 치료한 크렙시엘라 뉴모니아 내인성 안내염 2예

• 영문명: Two Cases of Klebsiella Pneumoniae Endogenous Endophthalmitis Treated with Sulperazone
• 발행기관: 대한안과학회
• 저자명: 이영록 김윤호 함경훈 신민철,Young-Rok Lee, M.D., Yun-Ho Kim, M.D., Kyoung-Hoon Hahm, M.D., Min-Cheol Shin, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number3, 554~559쪽, 전체 6쪽
• 주제분류: 인문학 > 역사학
• 파일형태: PDF
• 발행일자: 2005.03.31

영문 초록

Purpose: To report and review 2 cases of Klebsiella Pneumoniae endogenous endophthalmitis showing multi drug resistance that were treated with sulperazone. Methods: Sulperazone was administered to two patients with Klebsiella Pneumoniae endogenous endophthalmitis: a 51-year-old male with orbital cellulitis who showed no response to vancomycin, ceftazidime, and amikacin for 6days; and a 67-year-old female who showed no response to cefotaxime, and amikacin. Results: Proptosis and inflammation began to improve after changing to sulperazone. Therefore, enucleation and debridement could be avoided. Conclusions: Good results were obtained by use of Sulperazone which inactivates beta-lactamase irreversibly and which showed bactericidal effect to multi drug resistant Klebsiella Pneumoniae endogenous endophthalmitis.

키워드

Endogenous endophthalmitis, Klebsiella Pneumoniae, Sulperazone