휘틀(Hurthle) 세포 종양

• 영문명: Hurthle Cell Tumors of the Thyroid Gland
• 발행기관: 대한내분비외과학회
• 저자명: 서영진 전정수 김영혁 조현민 원용성 진형민 김준기 박우배 Young-Jin Suh M.D. Chung-Soo Chun M.D. Young- Hyug Kim M.D. Hyun-Min Cho M.D. Yong-Sung Won M.D. Hyung-Min Chin M.D. Jun-Gi Kim M.D. and Woo- Bae Park M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』1권1호, 89~91쪽, 전체 3쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2001.04.13

영문 초록

Purpose: Nodular lesions of the thyroid gland, composed predominantly of Hürthle cells, are so rare as to be difficult for pathologists to interpret properly and, consequently, for surgeons to treat appropriately. Our intent in evaluating these lesions was to try to establish pathologic and clinical criteria that could be used to differentiate more accurately between malignant and benign tumors. Methods: We retrospectively evaluated 5 patients presenting with Hürthle cell tumors over the past 10 years. We focused on the clinicopathological analysis correlated with the tumor size, the type of operation and the prognosis. Results: Five female patients were included in the study, their average age was 48.8 years (19∼69 years). One case was carcinoma and the other 4 were adenomas. Average size of the tumor was 3.34 cm in diameter. Total thyroidectomy was performed in two cases including the carcinoma case. None of them died as a result of the disease, nor had a recurrence. No preoperative study was useful in differentiating between malignancy and benignancy. Conclusion: Many more cases need to be evaluated to determine the exact biological behavior of the Hürthle cell tumor of the thyroid gland. Clinical and pathological factors are required for surgeons to decide the type of operation appropriate in order to avoid compromising the therapeutic goals. We recommend total thyroidectomy for tumors with the intraoperative frozen section raising the suspicion of malignancy and for those with diameters over 2.5 cm. (Korean J Endocrine Surg 2001;1:89-91)

키워드

갑상선, 휘틀세포, 종양,Thyroid, Hurthle cell, Tumor