갑상선의 호산구증 경화 점액표피양 암종: 원격전이를 동반한 증례보고

• 영문명: Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid: A Case Report with Distant Metastasis
• 발행기관: 대한내분비외과학회
• 저자명: 김주흥 김석모 홍순원1 장항석 박정수 Joo Heung Kim Seok-Mo Kim Soon Won Hong1 Hang-Seok Chang Cheong Soo Park
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』14권4호, 243~246쪽, 전체 4쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2014.12.30

영문 초록

Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland is a very rare carcinoma. We herein report on a case of SMECE with metastasis to bilateral lateral neck nodes, esophagus, and trachea. A 72-year-old woman presented with a neck mass found incidentally during a medical check-up. She had a history of cerebral stroke without sequelae 20 years ago and was taking aspirin regularly. The neck mass was confirmed as papillary thyroid carcinoma by fine needle aspiration biopsy. The patient underwent bilateral total thyroidectomy with central compartment and bilateral compartment lateral neck dissection. The right recurrent laryngeal nerve was sacrificed due to tumor invasion. The trachea wall and esophagus were also invaded by the cancer. Histologically, the tumor showed dense fibrohyaline stroma and a goblet cell, nested islands of squamoid cells, and marked stromal eosinophilia with perineural invasion and lymphovascular invasion, confirming the diagnosis of SMECE. After radiation therapy for three months, distant metastasis to the liver, lung, and bone were found on PET-CT. This case appears to be more aggressive than previously reported cases.

키워드

호산구증 경화 점액표피양 암종, 갑상선, 전이,Sclerosing mucoepidermoid carcinoma with eosinophilia, Thyroid gland, Metastasis