유두 갑상선암에서 종양 크기에 따른 림프절 전이 양상

• 영문명: Pattern of Cervical Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma according to Tumor Size
• 발행기관: 대한내분비외과학회
• 저자명: 김건 강현종 박경식 백남선 유영범 Gun Kim M.D. Hyun-Jong Kang M.D. Kyoung-Sik Park M.D. Nam-Sun Paik M.D. and Young-Bum Yoo M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』10권4호, 256~260쪽, 전체 5쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2010.12.30

영문 초록

Purpose: Prognosis of papillary thyroid carcinoma (PTC) is very favorable, but PTC frequently invade adjacent soft tissue and metastases to cervical lymph node. We evaluated the pattern of cervical neck lymph node metastasis in PTC according to tumor size. Methods: From August 2005 to January 2009, 353 patients were underwent surgery for PTC. Among these patients, total thyroidectomy with cervical neck lymph node dissection were done in 266 patients. We subdivided patients into four groups according to size and compared the clinicopathologic characters between groups. And we confirmed the factors affecting central neck node metastasis. Results: The mean age of patients of diagnosis was 49.1 years and female to male ratio was 5.8：1. Cervical lymph node metastasis were in 47.0% of the total cases. Cervical lymph node metastases and invasion to adjacent structure increased with tumor size. But, there were no significant differences in tumor size, invasion to adjacent structure, multifocality or bilaterality according to cervical lymph node metastasis. Early diagnostic age and sexuality were significantly related to cervical lymph node metastasis of PTC. Conclusion: PTC showed the aggressiveness with increasing tumor size. Tumor size was not related to cervical lymph node metastasis. These findings suggest that tumor size can help treat PTC, can`t be used by prediction factor of cervical lymph node metastasis. (Korean J Endocrine Surg 2010;10:256-260)

키워드

유두 갑상선암, 경부 림프절 전이, 종양 크기,Papillary thyroid carcinoma, Cervical lymph node metastasis, Tumor size