오매(Mume Fructus) 추출물의 혈행개선 효과

• 영문명: The Effects of Mume Fructus Extracts on Blood Flow Improvement
• 발행기관: 대한약학회
• 저자명: 박승희(Seung Hee Park) 박금주(Keum Ju Park) 김재기(Jae Ki Kim)
• 간행물 정보: 『약학회지』제53권 제5호 (2009년), 298~302쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.10.31

영문 초록

Mume Fructus extract is used in folk medicine in Eastern Asian countries including Korea. However, its therapeutic effect on thrombosis is not known. Mume Fructus methanol extract (ME) dose-dependently inhibited ADP-induced platelet aggregation and also exhibited about 130% fibrinolytic activity compared to the natto. Oral administration of ME to mice significantly extended tail-bleeding time. ME prolonged both aPTT and PT in human citrated plasma also. These results suggest that the methanol extract from Mume Fructus have antithrombosis activity.

키워드

Platelet Mume Fructus antithrombosis fibrinolysis anticoagulant