규산마그네슘의 최적합성조건

• 영문명: Optimal Sythesis Conditions of Magnesium Trisilicate
• 발행기관: 대한약학회
• 저자명: 신화우(Wha Woo Shin) 박인현(In Hyun Park)
• 간행물 정보: 『약학회지』제44권 제6호 (2000년), 545~551쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2000.12.30

영문 초록

Magilesium trisilicate was prepared by reacting Magnesium sulfate solution with Sodium silicate solution in this study. The optimum synthesis conditions base on the yield of the product were established by applying Box-Wilson experimental design. It was found that the optimum synthesis conditions of Magnesium trisilicate were as follows; Reacting temperature: 57-90oC, Concentration of reactant solution: 19.1-29.0%, Molar concentration ratio of two reactants: [Sod.sificate]/[Mg.sulfate] : 1.47-1.80, Temperature of washing water: 45-48oC, Drying temperature: 65-82oC. The antacidic capacity of the five Magnesium trisilicate samples which shows the maximum antacidic efficacy was tested by pharmacopeia acid consuming capacity test. The five Magnesium trisilicate samples were identified by chemical analysis.

키워드

Synthesis of Magnesium txisilicate Box-Wilson experimental design acid consuming capacity.