대나무 추출액의 항산화 작용과 미백작용

• 영문명: Anti-oxidant Activity and Whitening Activity of Bamboo Extracts
• 발행기관: 대한약학회
• 저자명: 송호선(Ho Sun Song) 문효진(Hyo Jin Moon) 박병언(Byoung Eun Park) 최방실(Bang Sil Choi) 이동자(Dong Ja Lee) 이지윤(Ji Yun Lee) 김창종(Chang Jong Kim) 심상수(Sang Soo Sin)
• 간행물 정보: 『약학회지』제51권 제6호 (2007년), 500~507쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.12.31

영문 초록

To investigate the possibility of development as a whitening agent using bamboo extracts (Phyllostachys nigra var. henonis), we measured DPPH assay, NBT/XO assay, intracellular ROS scavenging assay, tyrosinase assay and MSHinduced melanin production in B-16 cells. Bamboo extracts had dose-dependently anti-oxidant activity in DPPH, NBT/XO and intracellular ROS assay. Bamboo extracts appear to inhibit xanthine oxidase directly. Bamboo extracts inhibited not only purified tyrosinase activity but also inhibited tyrosinase activity and melanin production in B16 melanoma cells stimulated by 1 μM α-MSH. Anti-oxidant activity and cytotoxicity of ethyl acetate fraction was more potent than those of water fraction, whereas whitening effect of water fraction was stronger than ethyl acetate fraction. Therefore, these results suggest that water fraction of bamboo extracts may be useful for the development as whitening agents reducing cytotoxicity.

키워드

bamboo extracts anti-oxidant tyrosinase melanin