알릴티오필다진 유도체 합성 및 UV-C 조사에 대한 방어효과

• 영문명: Synthesis of Allylthiopyridazine Derivatives and their Protective Effects of UV-C Irradiation
• 발행기관: 대한약학회
• 저자명: 권순경(Soon Kyoung Kwon) 현지원(Jin Won Hyun)
• 간행물 정보: 『약학회지』제44권 제1호 (2000년), 9~15쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2000.02.28

영문 초록

Four 3-alkoxy-6-allylthiopyridazines and 3-chloro-6-allylthiopyfidazine were synthesized and their protective effects against oxidative stress and UV-C irradiation were tested. 3-Methoxy-6-allylth-iopyridazine and 3-ethoxy-6-allylthiopyridazine did not show protective effect on the oxidative stress but showed the strongest protective effect on UV-C irradiation among the tested compounds. Especially 500mcg/ml of the two compounds was the most effective concentration.

키워드

Allylthiopyridazine 1,2-diazine UV-C irradiation oxidative stress protective effect