율피.솔잎.호프의 수성 아세톤 추출물에 의한 Melanin 생성 억제 효과

• 영문명: Inhibitory Effects of Water-Acetone Extracts of Chestnut inner shell, Pine needle and Hop on The Melanin Biosynthesis
• 발행기관: 대한약학회
• 저자명: 양민진(Min Jin Yang) 김명길(Myung Gill Kim) 임세진(Se Jin Lim) 안형수(Hyung Soo Ann) 안령미(Ryoung Me Ahn)
• 간행물 정보: 『약학회지』제43권 제4호 (1999년), 494~501쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1999.08.28

영문 초록

The skin whitening effects of pine needle extract, hop extract and chestnut inner shell extract were evaluated both in vitro and in B 16 mouse melanoma cell lines. Each extracts significantly inhibited tyrosinase activity, dopa auto-oxidation and melanin biosynthesis in vitro and in B 16 cell lines. In vitro, hop extract inhibited melanin biosynthesis 15 times stronger than kojic acid at 10 mcg/ml concentration. Each extracts were stronger inhibitors of melanin biosynthesis than kojic acid in B 16 mouse melanoma cell at less than 4mcg/ml concentration. These results show that extracts of pine needle, hop and chestnut inner shell could be developed as skin whitening component of cosmetics.

키워드

Chestnut inner shell pine needie hop tyrosinase dopachrome melanin.