고삼추출물의 항균효과 (Ⅰ)

• 영문명: Antimicrobial Effect of the Extract of Sophora flavescens Ait (Ⅰ)
• 발행기관: 대한약학회
• 저자명: 조훈(Hoon Cho) 원성란(Sung Ran Weon) 양은영(Eun Yeong Yang) 김종수(Jong Soo Kim) 유일수(Il Soo You) 류도곤(Do Gon Ru) 이정호(Jeong Ho Lee) 강길웅(Kil Ung Kang) 백승화(Seung Hwa Baek)
• 간행물 정보: 『약학회지』제43권 제4호 (1999년), 419~422쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1999.08.28

영문 초록

In order to develop a antimicrobial agent, dried Sophora flavescens Ait. was extracted with several solvents, and then antimicrobial activity was investigated. The minimal inhibitory concentration(MIC) of the extracted substance against microorganisms were also examined. Antimicrobial activity of the initial methanol extract from the sample was the strongest compared to those of other solvent extracts such as H2O, n-hexane, chloroform, ethyl acetate and methanol. The methanol extract had strong growth inhibition activity against gram-postive bacteria (MIC, 25~50mcg/ml) such as B. subtilis and S. aureus. Among gram positive bacteria tested, B. subitlis was the most susceptible to the extracted substance. The antimicrobial activity of the methanol extract from the sample had strong growth inhibition activity against gram-negative bacteria such as P. aeruginosa (MIC, 25mcg/ml).

키워드

Sophora flavescens Ait antimicrobial actibity minimal inhibitory concentration.