팔선 양조용수의 세포독성 및 항암활성

• 영문명: The Cytotoxicity and Anititumor Acitivity of Palsun Brewing Water
• 발행기관: 대한약학회
• 저자명: 한두석(Du Seok Han) 한종현(Jong Hyun Han) 유화(Hwa Yu) 김지주(Ji Ju Kim) 강길웅(Kil Ung Kang) 백승화(Seung Hwa Baek)
• 간행물 정보: 『약학회지』제43권 제2호 (1999년), 173~179쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1999.04.27

영문 초록

In the present study, we have evaluated cytotoxic effects, antitumor activities and metastasis inhibitory effects of Palsun brewing water NIH 3T3 cells, human oral epitheloid carcinoma cells, and human skin melanoma cells. The light microscopic study showed morphological changes, AG-NOR (argyrophylic nucleolar organizer region) by silver chloride stain, and glycoprotein by PAS (periodic acid stain) reaction of the treated cells. Disruptions in cell organelles were deteminied by colorimetric methods;MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide) and SRB (sulforhodamine B protein) assays. These results suggest that Palsun Brewing Water retains no cytotoxic effects in NIH 3T3 cells and a growth-inhibitory activity in cancer cell lines.

키워드

Cytotoxic effect antitum or activity metastasis inhibitory effect palsun brewing water AGNOR PAS reaction MTT and SRB assays.