키토산 유도체의 담즙산 흡착 활성

• 영문명: The Bile Acid Absorption Activity of Chitosan Derivatives
• 발행기관: 대한약학회
• 저자명: 이아린(Ai Leen Lee) 이강만(Kang Man Lee)
• 간행물 정보: 『약학회지』제42권 제6호 (1998년), 572~575쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1998.12.31

영문 초록

Chitosan has been known to have hypocholesterolemic and hypolipidemic effects in animal studies. Chitosan also absorbs bile acids in vitro and in vivo, which might result in the hypocholesterolemic action. Trialkyl chitosan derivatives were prepared and tested for bile acid absorption activity in vitro. The derivatives showed enhanced absorption capacities which were comparable to cholestyramine.

키워드

Chitosan N-trialkyl chitosans bile acid absorption.