승마 추출물의 항알레르기 효과

• 영문명: Antiallergic Effect of Cimicifuga heracleifolia Extract
• 발행기관: 대한약학회
• 저자명: 신태용(Tae Yong Shin) 서형만(Hyung Man Seo) 채병숙(Byeong Suk Chae)
• 간행물 정보: 『약학회지』제42권 제4호 (1998년), 403~407쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1998.08.31

영문 초록

Effects of the aqueous extract of Cimicifuga heracleifolia (CHAE) on the allergic reactions were investigated. CHAE inhibited systemic anaphylaxis induced by compound 48/80 in mice dose-dependently. Especially, CHAE inhibited compound 48/80-induced systemic anaphylaxis 100% with a dose of 0.5mg/g body weight. CHAE significantly inhibited serum histamine levels induced by compound 48/80. CHAE inhibited histamine release from the rat peritonea] mast cells activated by compound 48/80 or anti-DNP IgE. Our studies provide evidence that CHAE will be beneficial in the treatment of anaphylias.

키워드

Cimicifuga heracleifolia Anaphylaxis Compound 48/80 Anti-dinitrophenyl IgE Histamine Mast cells.