음양곽분획물이 생쥐의 면역반응에 미치는 영향

• 영문명: Effects of Epimedii Herba Fraction on Response in ICR Mice
• 발행기관: 대한약학회
• 저자명: 김정훈(Joung Hoon Kim) 김인훈(In Hoon Kim) 채병숙(Byeong Suk Chae) 강태욱(Tae Wook Kang) 박찬봉(Chan Bong Park) 안영근(Young Keun Ahn)
• 간행물 정보: 『약학회지』제40권 제2호 (1996년), 230~237쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1996.04.30

영문 초록

The fractions of Epimedii Herba were examined for the immunological effects in ICR mice. Mice were divided into 4 groups and administered orally the fractions of Epimedii Herba for 10 days. The results of this study were summarized as following: (1) The fraction 1 (EtOAc layer) administered group as compared with control group significantly decreased spleen weight, Arthus reaction and hemagglutination (HA) titer but significantly increased circulating white blood cells (WBC). (2) The fraction 2 (H20 layer) administered group as compared with control group significantly decreased liver weight, Arthus reaction and HA titer but significantly increased WBC. (3) The fraction 3 (ppt) administered group as compared with control group significantly increased liver weight, thymus weight rate, delayed type hypersensitivity, phagocytic activity and WBC. The results showed that Frs. 1 and 2 administered groups reduced humoral immune response but increased WBC, and that Fr. 3 administered group increased cell-mediated immune response, phagocytic activity and WBC.

키워드

Fractions of Epimedii Herba immunological response SRBC ICR mice.