항바이러스제 Transdermal Patch의 제조와 평가

• 영문명: Evaluation of Transdermal Patch for Antiviral Agen
• 발행기관: 대한약학회
• 저자명: 최승호(Seung Ho Choi) 김종갑(Johng Kap Kim)
• 간행물 정보: 『약학회지』제34권 제6호 (1990년), 429~433쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1990.12.28

영문 초록

Transdermal patches and polymer membrane were prepared and evaluated for their ability to antiviral agent in vitro. The membrane perpared with styrene and HEMA by 0.5 and 10% of styrene composition. And the transdermal patches were fabricated with this membrane and silastic silicone sheeting. The antiviral agents used were ACV, BVDU and FEAU. The higher HEMA content membranes exhibited relatively high release rate of each drug. Permeation was enhanced by increasing of drug concentration. The parameters of each drug in diffusion experiment with styrene-HEMA membrane were investigated.

키워드

Kvaluation transdermal patch polymer membrane