DNA/RNA Hybridization에 의한 흰쥐의 Transferrin mRNA 분포에 관한 연구

• 영문명: Localization of Transferrin mRNA in Rat by DNA/RNA Hybridization
• 발행기관: 대한약학회
• 저자명: 김세은(Se Eun Kim) 김선여(Sun Yeou Kim) 박미정(Mi Jung Park) 송진호(Jin Ho Song) 이은방(Eun Bang Lee) 이흔파(Heun Pa Lee) 김영중(Young Choong Kim)
• 간행물 정보: 『약학회지』제33권 제5호 (1989년), 300~307쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1989.10.28

영문 초록

Expression of transferrin gene in various organs of rat was studied using rat transferrin cDNA. The hybridization method of [35S]-labeled transferrin cDNA with transferrin mRNA in cytoplasmic preparations was used to measure the level of transferrin mRNA. The rat from 15-day old fetus to 21-day old postnatal were employed as an animal model. In the liver, the level of transferrin mRNA increased with increasing age. However, the level of transferrin mRNA in brain was significantly lower than that in liver and the level did not increase with age.

키워드

Transferrin cDNA plasmid transferrin mRNA cytoplasmic preparations hybridization.