토복령(Similax china)의 Steroid Saponin이 돌연변이원성에 미치는 영향

• 영문명: Mutagenic Effect of Steroidal Saponins from Smilax china Rhizomes
• 발행기관: 대한약학회
• 저자명: 김성환(Sung Whan Kim) 손건호(Kun Ho Son) 정규찬(Kyu Charn Chung)
• 간행물 정보: 『약학회지』제33권 제5호 (1989년), 285~289쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1989.10.28

영문 초록

Pontential mutagenic and antimutagenic activities of four steroidal saponins from Smilax china rhizomes were investigated. These saponins did not reveal mutagneicity in the Ames and SOS umu test. For antimutagenic activity by SOS umu test, two spirostanol glycosides, dioscin and gracillin, inhibited the activity of beta-galactosidase induced by AF-2, but their prototype furostanol glycosides did not show this activity.

키워드

Smilax china Rhizome steroidal saponin mutagenicity