2-치환-1-Cyclohexenyl-1-acetic acid의 브롬락톤화 반응

• 영문명: Bromolactonization of 2-Substituted-1-Cyclohexenyl-1-acetic acid
• 발행기관: 대한약학회
• 저자명: 주상섭(Sang Sup Jew)
• 간행물 정보: 『약학회지』제33권 제3호 (1989년), 206~210쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1989.06.25

영문 초록

Bromolactonization of 2-Substituted-1-cyclohexenyl-1-acetic acid (1) with 1,3-dibromo-5,5-dimethylhydantoin (dibromantin) in N,N-dimethylformamide gave the corresponding gamma-bromo-beta-lactone (2) and beta-bromo-gamma-lactone (3). The effect of the substituents, the reaction temperature, and the solvent on the regioselectivity was discussed.

키워드

bromolactonization 2-substituted-1-cyclohexenyl-1-acetic acid gamma-bromo-β-lactone β-bromo-gamma-lactone