주약의 혼합비율이 정제의 함량균일성에 미치는 영향

• 영문명: Effect of Mixing Ratios of Active Ingredient on Content Uniformity of Tablets
• 발행기관: 대한약학회
• 저자명: 김길수(Kil Soo Kim)
• 간행물 정보: 『약학회지』제31권 제5호 (1987년), 343~346쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1987.10.30

영문 초록

The effect of mixing ratios of active ingredient on the content uniformity of tablets was studied using caffeine as active ingredient and hydroxypropyl starch as diluent. In the case that caffeine content was not more than 1%, the standard deviation of individual tablet assays was inversely proportional to caffeine content. In the case of more than 1%, the standard deviation was constant independently of caffeine content. In the case that the designed tablet weight was not more than 200mg, the standard deviation of individual tablet assays was inversley proportional to tablet weight designed. In the case of more than 200mg, it was constant and the results for weight variation against the designed weight showed same tendency.