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• 영문명: Determination of Voglibose in Pharmaceutical Preparation by Gas Chromatography
• 발행기관: 대한약학회
• 저자명: 이재윤(Jae-Yoon Lee) 안문규(Moon-Kyu Ahn)
• 간행물 정보: 『약학회지』제47권 제6호 (2003년), 352~355쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2003.12.31

영문 초록

Voglibose is a new antidiabetic agent currently being developed by the research and development division of Takeda chemical industries Ltd. In japan. Basic research for the determination of oglibose in pharmaceutical preparation by gas chromatography. This method utilizes voglibose to give its acyl compound with acetyl anhydride in pyridine solution. The calibration curve for rvoglibose was linear over the concentration range of 0.08~0.32 μg/μl with correlation coefficient of 0.996. The detection limit for voglibose was 0.016 μg/μl and the result of recovery test was 101.6% with relative standard deviation of 2.0% by standard addition method.

키워드

voglibose gas chromatography antidiabetic agent.